The best supplements with alpha-lipoic acid - Top 5 2026
Alpha-Lipoic Acid (ALA, for Alpha-Lipoic Acid) is a naturally occurring compound with powerful antioxidant properties. Also known as thioctic acid, it plays a key role in cellular energy metabolism, supporting energy production processes in the mitochondria. Its unique ability to neutralize free radicals and protect cells from oxidative stress makes it an extremely versatile antioxidant. What's more, alpha-lipoic acid can regenerate other antioxidants, such as vitamin C, E, coenzyme Q10 and glutathione, enhancing their effectiveness. It also acts as a heavy metal chelator, promoting detoxification of the body. In our ranking you will find the best alpha-lipoic acid supplements to try in 2026. Check out our TOP 5 and choose the perfect product for you!
The ranking factors we took into account are:
- Quality
- Capsule size
- Dose
- Price
- Price. Effectiveness
- Purity of formulation
- Effects
What qualities should a good alpha-lipoic acid have?
High purity: A good alpha-lipoic acid should be free of impurities and other unnecessary additives, which ensures its effectiveness and safety of use.
The right dose. Appropriate dosage: It is important that the product contain the effective dose of alpha-lipoic acid that is recommended to support health, usually between 300 and 600 mg per day.
Stability of form: Alpha-lipoic acid should be available in a stable form to maintain its antioxidant properties throughout its shelf life.
Good bioavailability: A good alpha-lipoic acid supplement should be easily absorbed by the body, which increases its effectiveness in neutralizing free radicals and supporting energy metabolism.
No unnecessary additives: The product should be free of artificial colors, preservatives and other unnecessary ingredients that may reduce its quality.
Light-protective packaging: Alpha-lipoic acid is sensitive to light, so a good product should be stored in a dark, airtight container to maintain its stability and effectiveness.
Take a look at the ranking for the best alpha-lipoic acid:
Alpha-lipoic acid from Nutridome is a dietary supplement available in easy-to-swallow capsules. The product contains a high but safe dose of ALA, which translates into its effectiveness and comprehensive effects. Our testers appreciated the simplicity of the formulation and the fact that the supplement is vegan-friendly. It contains no unnecessary additives, making it an excellent support for the body. Alpha-lipoic acid helps control blood sugar levels by increasing insulin sensitivity and improving glucose tolerance. It also acts as a powerful antioxidant, supporting detoxification and cell regeneration. The capsules are easy to take, and one packet lasts for 30 days of supplementation. Nutridome offers high-quality alpha-lipoic acid, which is excellent for supporting the body's health and is a great choice for anyone planning ALA supplementation.
Now Foods' alpha-lipoic acid is enriched with vitamins C and E, which significantly enhances its antioxidant properties. ALA has the ability to regenerate other antioxidants, such as vitamins C and E, making this supplement extremely effective in protecting the body from oxidative stress. Regular use can delay skin aging and protect against various ailments caused by free radicals. In addition, alpha-lipoic acid can support the treatment of diabetes, heart disease and obesity. The recommended dosage is one capsule twice a day, and the biggest downside is the large capsule size and the rather high price.
Alpha-lipoic acid R-ALA by Aliness is a dietary supplement that, like the Now Foods product, offers powerful antioxidant activity. Alpha-lipoic acid in this form effectively supports the regeneration of other antioxidants, such as vitamins C and E, which helps protect the body from free radical damage. Regular use of the Aliness supplement can support the treatment of diabetes, heart disease and support the maintenance of a healthy weight. Although the effects of this product are similar to alpha-lipoic acid offered by Now Foods, the Aliness supplement is significantly more expensive, making it rank lower in our ranking.
A vegan dietary supplement from Solgar provides 200 mg of alpha-lipoic acid in each capsule. ALA acts as a powerful antioxidant that helps prevent inflammation and slows down the body's aging process. In addition, it enhances the effects of other antioxidants such as glutathione, vitamin C and vitamin E. Regular use of Solgar capsules supports glucose metabolism, improves tissue sensitivity to insulin and supports the proper functioning of the nervous system. The manufacturer recommends taking one capsule twice a day. Unfortunately, the ALA dosage is low and the package runs out quickly, which, with the high price, makes this proposition not very cost-effective.
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My Vita Silver R-ALA is an alpha lipoic acid available in capsule form. Although alpha lipoic acid is designed to protect cells from free radicals, our testers found the protection offered by this supplement to be insufficient due to its low ALA content. After long-term, systematic supplementation, some benefits can be seen in fat metabolism and blood sugar regulation, but these effects are rather average. Our testers did not notice a significant effect on the body's detoxification process when using this product. In addition, the price of the supplement seems high relative to the dose, and the capsules themselves are difficult to swallow.
