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The best sodium butyrate supplements - TOP 5 in 2025

The best sodium butyrate supplements - TOP 5 in 2025


Sodium butyrate, formed by the fermentation of carbohydrates by intestinal bacteria, is crucial for the health of the digestive tract. It is a source of butyric acid, which nourishes and protects the intestinal mucosa, being an essential ingredient in the prevention and treatment of diseases such as irritable bowel syndrome (IBS) and intestinal flora disorders. Sodium butyrate also has an anti-inflammatory effect, which helps to reduce oxidative stress and relieve intestinal inflammation. The recommended daily dose of this ingredient is 200-300 mg of butyric acid. If you are struggling with gastrointestinal issues and want to support your health, take a look at our ranking of the best top 5 supplements with sodium butyrate.

Theranking factors we took into account are:

  • Effectiveness
  • Sodium butyrate/butyric acid content
  • Ease of use
  • Price
  • Efficiency
  • Undesirable effects
  • Composition

What qualities to look for in a good sodium butyrate supplement?

Butyricacid content: A good sodium butyrate supplement should contain a high concentration of butyric acid, which is crucial for effective support of gut health and overall digestive health.

Composition: Supplements without artificial additives, colours or preservatives are preferred, ensuring safety and health benefits without unwanted side effects.

Envelope: Optimised release of active ingredients in the gut, not the stomach, which increases the effectiveness of the supplement by protecting the butyric acid from degradation during digestion.

Vegan: The supplement formula should be suitable for those on a vegan or vegetarian diet, containing no gelatine or other animal-derived ingredients.

Take a look at our ranking of the best supplements with sodium butyrate:

4.98
Composition: 4.9
Butyric acid content: 5
Coverage: 5
Effectiveness: 5

Nutridome's sodium butyrate capsules are distinguished by their exceptionally high butyric acid content of 500 mg per daily dose, which was immediately appreciated by those testing the product. They emphasised the natural composition and the vegan nature of the capsules, which gained them great approval. With regular use, the supplement significantly improves the functioning of the digestive system and provides relief from various stomach problems. Users have also noted that Nutridome sodium butyrate is particularly helpful for those suffering from irritable bowel syndrome or intestinal flora problems, offering effective anti-inflammatory action and symptom relief. It also supports the digestive system after antibiotics. The capsules are easy to consume and have no side effects, which overall makes for a well-deserved win in today's list.

4.35
Composition: 4.4
Butyric acid content: 4.5
Coverage: 4.2
Effectiveness: 4.3

Sodium Butyrate Forte by Health Labs came second in our ranking of digestive and immune support supplements. It is a vegan product that has gained recognition for its natural composition and its effectiveness in regenerating natural intestinal flora. Through the use of encapsulation technology, butyric acid is released directly in the gut, increasing the effectiveness of the supplement. Test subjects appreciated its ability to restore the microbiological balance in the digestive tract. Nevertheless, due to the need for storage within a certain temperature range and the relatively high price, this product may not be the first choice for everyone. In addition, Sodium Butyrate Forte is recommended to be used under medical supervision, which may be an additional limitation for potential users.

4.15
Composition: 4.3
Butyric acid content: 3.9
Coverage: 4.3
Effectiveness: 4.1

The SFD-branded supplement came third in our ranking, largely due to its butyric acid content of only 170 mg per 550 mg of sodium butyrate per dose. Despite this, users were pleased with the natural composition and packaging performance. The product is designed to support intestinal health and helps to combat common digestive problems such as irritable bowel syndrome and inflammatory diseases. The large size of the capsules and their unsuitable formulation for vegans were the main problems reported by our group of testers.

4.08
Composition: 4.2
Butyric acid content: 3.8
Coverage: 4.1
Effectiveness: 4.2

Sodium butyrate by Ostrovit is quite popular on the market due to its affordable price and the number of capsules per pack. The composition of the supplement is simple and the capsule's casing is free of substances of animal origin, so it is suitable for vegans and vegetarians. In terms of action, it is similar to the item above. Despite its sizable sodium butyrate content, the amount of butyric acid is much, much less, which translates into lower efficacy than supplements with butyrate, where the acid is more concentrated. As a basic butyrate supplement option, the supplement will work well, but for those seeking stronger support, its effect may be too weak.

3.88
Composition: 3.9
Butyric acid content: 3.7
Coverage: 4
Effectiveness: 3.9

Sodium Butyrate by Aliness came last in our ranking of supplements to support digestive health. This does not mean that it is a bad product, but our group had some reservations about it. The large capsule size may be a problem for some users. Aliness sodium butyrate is designed to support bowel function and prevent common digestive complaints. The product packaging is efficient, but the butyric acid content of the daily serving is only 170 mg per 550 mg of sodium butyrate, which does not stand out from the competition, especially given the higher price of the product. In practice, it is a very similar product to the item above, but available at a higher price.

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Maria Buterez
Maria Buterez Author

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