The best supplements for insulin resistance - TOP 5 in 2025
Insulin resistance, is a condition that affects an increasing number of people worldwide. Insulin resistance leads to metabolic disorders that can result in type 2 diabetes, heart disease and other serious health problems. Therefore, supplementation with the right ingredients can provide important support in the fight against insulin resistance. In this ranking, we take a look at the most effective supplements that can help improve insulin sensitivity, blood sugar regulation and overall metabolic functioning.
The ranking factors we considered were:
- Increased insulin sensitivity
- No side effects
- Lowering of sugar levels
- Safety
- Support for liver health
- Composition
- User opinions
What ingredients to look for in good products for insulin resistance?
Berberine: is a natural compound found in plants such as periwinkle, goldenrod and barberry. Research shows that berberine increases insulin sensitivity and helps regulate glucose metabolism.
Chromium: helps to increase insulin sensitivity, which may be beneficial for people with insulin resistance.
Magnesium: plays a key role in many metabolic processes, including glucose and insulin metabolism.
Vitamin D: vitamin D deficiency is associated with metabolic disorders, including insulin resistance. Vitamin D supplementation may help improve insulin sensitivity.
Take a look at our ranking of the best products for insulin resistance:
The dietary supplement Berberine NUTRIDOME, is a natural support for people with blood sugar disorders. It has a beneficial effect on the liver and metabolic processes. In addition to its effects on sugar levels and weight loss, it has the ability to protect cells from oxidative stress. It has anti-cancer and anti-ageing effects. It is also an effective supplement in regulating blood pressure. Scientific evidence suggests that Berberine can promote weight loss by regulating lipogenic genes. It increases insulin sensitivity and helps improve glucose utilisation by the body's cells. It is valued by people with insulin resistance, who often consider it as a natural replacement for metformin. In addition, berberine reduces complications of type 2 diabetes. The insulin resistance supplement from Nutridome comes in the form of easy-to-swallow capsules and lasts for a month's treatment.
Health Labs BalanceMe, helps to reduce symptoms of insulin resistance and metabolic syndrome, maintain normal blood glucose levels and strengthen insulin sensitivity. It combines four ingredients to support sugar management: barberry root extract, Ceylon cinnamon bark extract, myo-inositol and alpha-lipoic acid. Among other things, these ingredients help to improve blood glucose control. The dietary supplement provides support for those aiming to maintain proper sugar levels. The product helps to restore insulin sensitivity and counteracts the development of type 2 diabetes. The supplement is sufficient for a month's treatment, at a rather high price. It is necessary to take 3 capsules a day, which can be a bit tedious.
Aliness Berberine Sulphate helps to regulate blood glucose levels and maintain adequate insulin sensitivity, which contributes to digestive health. Additionally, berberine is known to have a positive effect on insulin resistance. Other beneficial properties of berberine extract include positive effects on skin and liver health. Aliness Berberine Sulphate is particularly recommended for people who consume higher amounts of carbohydrates and wish to take care of a healthy glucose-lipid balance. The price of the supplement is quite favourable for a single-ingredient supplement. However, you can find cheaper alternatives with equal or higher concentrations of berberine. Such as our ranking leader.
Insuresin, is a set of supplements for people with reduced insulin sensitivity. It consists of sachets for preparing a suspension and capsules for swallowing. The sachets contain chicory inulin and myo-inositol, which belongs to the B vitamins and plays an important role in improving glucose transport to insulin-sensitive cells. The formula also contains berberine and ginger, which normalise glucose levels and improve glucose transport into cells. The addition of vitamin D supports the functioning of the immune system, and vitamin B12 contributes to reducing feelings of fatigue and tiredness. The form of supplementation in this kit is quite engaging and strenuous. It is important to be aware of the correct sequence and subsequent doses.
Kenay Berberine, is a supplement that will work well as a dietary supplement for both active people and those who regularly take care of their health. Berberine is a bioactive substance derived from the common barberry and is valued in natural medicine. It is often recommended for people who struggle with overweight, insulin resistance or obesity. Berberine helps to increase tissue sensitivity to insulin. And improving this sensitivity can help improve glucose utilisation by the body's cells. Berberine may also affect the composition and function of the gut microflora, which is important for glucose metabolism and insulin resistance. Berberine also shows anti-inflammatory properties. The supplement, despite its large capacity, is very expensive. It is also important to remember that natural supplements have a rather short shelf life once opened.
